Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 11/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616645 | 0.85 | MRGPRX4 (0.45) | MRGPRX4FFAR4FFAR1NPC1MAPT | |
| SCHEMBL16273633 | 0.84 | MRGPRX4 (0.46) | MRGPRX4FFAR4FFAR1NPC1MAPT | |
| SCHEMBL17616649 | 0.81 | FFAR1 (0.39) | MRGPRX4GABRA1GABRB2FFAR4CD274 | |
| SCHEMBL17616620 | 0.80 | MRGPRX4 (0.40) | MRGPRX4GABRA1GABRB2FFAR4FFAR1 | |
| SCHEMBL17616598 | 0.79 | FFAR4 (0.41) | MRGPRX4GABRA1GABRB2FFAR4FFAR1 | |
| SCHEMBL16273629 | 0.79 | GABRA1 (0.40) | GABRA1GABRB2MAPT | |
| SCHEMBL17616646 | 0.79 | L3MBTL1 (0.45) | GABRA1GABRB2FFAR4FFAR1MAPT | |
| SCHEMBL17677487 | 0.78 | MRGPRX4 (0.45) | MRGPRX4NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL16273628 | 0.77 | MRGPRX4 (0.40) | MRGPRX4FFAR4FFAR1NPC1MAPT | |
| SCHEMBL19736986 | 0.77 | RAB9A (0.57) | MRGPRX4FFAR4CD274NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |