Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987586 | 0.82 | MRGPRX4 (0.38) | MRGPRX4FFAR4MAPTL3MBTL1MEN1 | |
| SCHEMBL19987532 | 0.81 | FFAR1 (0.33) | MRGPRX4FFAR4MAPTTDP1L3MBTL1 | |
| SCHEMBL19987563 | 0.79 | MRGPRX4 (0.44) | MRGPRX4FFAR4MAPTSMN1; SMN2TDP1 | |
| SCHEMBL19987565 | 0.79 | ELANE (0.35) | MAPTTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL19987600 | 0.76 | MRGPRX4 (0.44) | MRGPRX4FFAR4MAPTSMN1; SMN2CD274 | |
| SCHEMBL19987543 | 0.76 | MAOB (0.43) | FFAR4MAPTSMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL21317985 | 0.76 | FFAR1 (0.34) | FFAR4MAPTTDP1L3MBTL1MEN1 | |
| SCHEMBL16273703 | 0.75 | MRGPRX4 (0.37) | MRGPRX4FFAR4MAPTCYP2C9CYP2C19 | |
| SCHEMBL16273652 | 0.74 | TP53 (0.53) | MRGPRX4MAPTCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL19987559 | 0.72 | MRGPRX4 (0.34) | MRGPRX4MAPTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |