Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987565 | 0.86 | ELANE (0.35) | GAAALDH1A1HDAC8MAPTTHRB | |
| SCHEMBL18831493 | 0.81 | MRGPRX4 (0.38) | MRGPRX4HDAC6ALDH1A1HDAC8MAPT | |
| SCHEMBL19987563 | 0.79 | MRGPRX4 (0.44) | MRGPRX4TP53ALDH1A1MAPTNPC1 | |
| SCHEMBL19987543 | 0.76 | MAOB (0.43) | GAAALDH1A1MAPTSMN1; SMN2FFAR4 | |
| SCHEMBL19987564 | 0.76 | MRGPRX4 (0.35) | MRGPRX4ALDH1A1MAPTSMN1; SMN2FFAR4 | |
| SCHEMBL19987586 | 0.76 | MRGPRX4 (0.38) | MRGPRX4TP53GAAALDH1A1MAPT | |
| SCHEMBL23506115 | 0.73 | HDAC8 (0.35) | MRGPRX4HTTGAAALDH1A1HDAC8 | |
| SCHEMBL16273696 | 0.73 | MRGPRX4 (0.49) | MRGPRX4TP53HTTGAAMAPT | |
| SCHEMBL16273719 | 0.72 | MRGPRX4 (0.80) | MRGPRX4TP53HTTALDH1A1CLCN2 | |
| SCHEMBL21317985 | 0.72 | FFAR1 (0.34) | GAAALDH1A1MAPTTHRBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |