Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987600 | 0.86 | MRGPRX4 (0.44) | ALDH1A1MAPTGAATHRBHDAC8 | |
| SCHEMBL19987563 | 0.81 | MRGPRX4 (0.44) | ALDH1A1MAPTTDP1L3MBTL1 | |
| SCHEMBL19987564 | 0.79 | MRGPRX4 (0.35) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL19987543 | 0.79 | MAOB (0.43) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL19987586 | 0.78 | MRGPRX4 (0.38) | ALDH1A1MAPTMEN1GAATHRB | |
| SCHEMBL16273699 | 0.74 | KMT2A (0.40) | ELANEF2CTSGALDH1A1MAPT | |
| SCHEMBL21317985 | 0.74 | FFAR1 (0.34) | ALDH1A1MAPTMEN1GAATHRB | |
| SCHEMBL19987598 | 0.73 | CDK4 (0.48) | ELANEF2ALDH1A1MAPTGAA | |
| SCHEMBL19987532 | 0.73 | FFAR1 (0.33) | ALDH1A1MAPTMEN1GAATHRB | |
| SCHEMBL16273659 | 0.72 | MRGPRX4 (0.59) | ELANEF2ALDH1A1KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |