Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987563 | 0.82 | MRGPRX4 (0.44) | MRGPRX4FFAR4FFAR1ALDH1A1L3MBTL1 | |
| SCHEMBL19987532 | 0.82 | FFAR1 (0.33) | MRGPRX4FFAR4FFAR1ALDH1A1L3MBTL1 | |
| SCHEMBL19987564 | 0.82 | MRGPRX4 (0.35) | MRGPRX4FFAR4ALDH1A1SLC1A5L3MBTL1 | |
| SCHEMBL21317985 | 0.82 | FFAR1 (0.34) | FFAR4FFAR1PARP10PARP15PARP14 | |
| SCHEMBL19987543 | 0.80 | MAOB (0.43) | FFAR4FFAR1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL19987565 | 0.78 | ELANE (0.35) | ALDH1A1SLC1A5L3MBTL1MAPTKDM4E | |
| SCHEMBL19987600 | 0.76 | MRGPRX4 (0.44) | MRGPRX4FFAR4ALDH1A1MAPTTP53 | |
| SCHEMBL16273712 | 0.75 | MRGPRX4 (0.40) | MRGPRX4MCL1PTGDR2FFAR4FFAR1 | |
| SCHEMBL16273651 | 0.75 | MRGPRX4 (0.53) | MRGPRX4MCL1PTGDR2ALDH1A1TP53 | |
| SCHEMBL18831667 | 0.74 | MAPT (0.37) | MRGPRX4FFAR4ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |