Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16273703 | 0.79 | MRGPRX4 (0.37) | MCL1HTR6MAPTL3MBTL1TDP1 | |
| SCHEMBL19987568 | 0.77 | PTGDR2 (0.41) | MCL1MAPTMAPK1KMT2AALDH1A1 | |
| SCHEMBL16273652 | 0.75 | TP53 (0.53) | MCL1MAPTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16273612 | 0.75 | CYP3A4 (0.39) | HTR6MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL19987538 | 0.74 | PTGDR2 (0.41) | MCL1MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL19987555 | 0.73 | PTGDR2 (0.46) | MCL1MAPTMRGPRX4PTGDR2KDM4E | |
| SCHEMBL16273625 | 0.73 | MAOB (0.49) | MAPTL3MBTL1MAPK1KMT2AALDH1A1 | |
| SCHEMBL11565580 | 0.69 | IDO1 (0.38) | MCL1ALDH1A1PKMABCB1 | |
| SCHEMBL19987564 | 0.69 | MRGPRX4 (0.35) | HTR6MAPTL3MBTL1TDP1MEN1 | |
| SCHEMBL16273753 | 0.68 | HTR6 (0.35) | HTR6MAPTL3MBTL1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |