Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987555 | 0.90 | PTGDR2 (0.46) | PTGDR2FFAR4FFAR1MCL1KDM4E | |
| SCHEMBL18831445 | 0.83 | SLC22A12 (0.36) | PTGDR2FFAR4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18831621 | 0.82 | SLC22A12 (0.41) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL18831528 | 0.79 | MET (0.37) | ALDH1A1NPSR1 | |
| SCHEMBL16273701 | 0.78 | PTGDR2 (0.39) | PTGDR2FFAR4ALDH1A1CDK4CCND1 | |
| SCHEMBL19987567 | 0.77 | MCL1 (0.37) | PTGDR2FFAR4ALDH1A1ABCB1KMT2A | |
| SCHEMBL19987538 | 0.77 | PTGDR2 (0.41) | PTGDR2FFAR4ALDH1A1ABCB1KMT2A | |
| SCHEMBL16273716 | 0.75 | TP53 (0.56) | PTGDR2FFAR4ALDH1A1MCL1 | |
| SCHEMBL19987592 | 0.75 | LTB4R (0.43) | PTGDR2FFAR4ALDH1A1FFAR1KDM4E | |
| SCHEMBL16273632 | 0.75 | CYP3A4 (0.37) | PTGDR2FFAR4ALDH1A1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |