Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987568 | 0.90 | PTGDR2 (0.41) | PTGDR2FFAR4FFAR1MCL1MAPT | |
| SCHEMBL16273702 | 0.79 | MRGPRX4 (0.42) | PTGDR2MRGPRX4FFAR4FFAR1NPC1 | |
| SCHEMBL18831528 | 0.78 | MET (0.37) | MRGPRX4GAAPTGER1 | |
| SCHEMBL16273715 | 0.76 | MRGPRX4 (0.68) | PTGDR2MRGPRX4FFAR4FFAR1NPC1 | |
| SCHEMBL16273628 | 0.76 | MRGPRX4 (0.40) | PTGDR2MRGPRX4FFAR4FFAR1NPC1 | |
| SCHEMBL16273707 | 0.74 | RAB9A (0.51) | PTGDR2MRGPRX4NPC1HTTMAPT | |
| SCHEMBL18831445 | 0.74 | SLC22A12 (0.36) | PTGDR2MRGPRX4FFAR4MAPT | |
| SCHEMBL19987567 | 0.73 | MCL1 (0.37) | PTGDR2MRGPRX4FFAR4MCL1TP53 | |
| SCHEMBL18831621 | 0.73 | SLC22A12 (0.41) | MRGPRX4MAPTHPGDKDM4E | |
| SCHEMBL19987538 | 0.73 | PTGDR2 (0.41) | PTGDR2FFAR4MCL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |