SCHEMBL19987932

SCHEMBL19987932

O=C(c1ccc(CCC(Cl)Cl)cc1)c1ccc(CCC(Cl)Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 1/20 0.42
SRD5A2 P31213 6/20 0.41
S1PR1 P21453 1/20 0.40
CNR2 P34972 2/20 0.40
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
MAPT P10636 1/20 0.39
PKM P14618 1/20 0.39
HPGD P15428 1/20 0.39
MMP12 P39900 1/20 0.39
MMP13 P45452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2878724 0.82 GFER (0.36) HTTESR1ESR2MMP12MMP13
SCHEMBL27389478 0.78 KMT2A (0.50) SRD5A2HTTHPGDMEN1KMT2A
SCHEMBL27696370 0.76 ALDH1A1 (0.54) SRD5A2HTTLMNAMAPTHPGD
SCHEMBL10594828 0.76 CNR2 (0.46) SRD5A2S1PR1CNR2HTTLMNA
SCHEMBL12517713 0.75 MMP12 (0.46) BDKRB2SRD5A2S1PR1HTTLMNA
SCHEMBL253829 0.73 HTT (0.53) SRD5A2HTTHPGDMEN1KMT2A
SCHEMBL9188055 0.73 SMN1; SMN2 (0.43) MAPTMEN1KMT2ASMN1; SMN2MAPK1
SCHEMBL14244548 0.72 THRA (0.49) SRD5A2S1PR1CNR2LMNAESR1
SCHEMBL11827641 0.72 ALDH1A1 (0.48) SRD5A2HTTLMNAMAPTHPGD
SCHEMBL15392359 0.72 ALDH1A1 (0.48) SRD5A2HTTLMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE (US) 2026-02-24 US disclosed
EP-3299514-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE EUROPE GMBH (DE) 2024-11-06 EP disclosed
CN-110835506-B Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2022-11-04 CN disclosed
CN-107869054-B Adhesive-reinforced textile, method for the production thereof and use thereof 约翰斯曼维尔欧洲有限公司 2022-05-03 CN disclosed
EP-3779015-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE (US) 2021-12-08 EP disclosed
US-10934460-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2021-03-02 US disclosed
EP-3779015-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville (US) 2021-02-17 EP disclosed
CN-110835506-A Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2020-02-25 CN disclosed
US-20200056327-A1 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE 2020-02-20 US disclosed
US-10472546-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2019-11-12 US disclosed
US-20180086951-A1 BINDER-CONSOLIDATED TEXTILE FABRICS AND METHODS OF THEIR MANUFACTURE AND USE JOHNS MANVILLE 2018-03-29 US disclosed
EP-3299514-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville Europe GmbH (DE) 2018-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use SEM1, SMCHD1, SMC4 BDKRB2 4327/4885SRD5A2 3911/4885S1PR1 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.