Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8966754 | 0.95 | EPHX1 (0.41) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL4243546 | 0.93 | EPHX1 (0.44) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL4785319 | 0.86 | SIGMAR1 (0.43) | EPHX1DPP4SIGMAR1TP53LMNA | |
| SCHEMBL17163913 | 0.85 | — | — | |
| SCHEMBL8642196 | 0.85 | SIGMAR1 (0.47) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL28430462 | 0.80 | EPHX1 (0.44) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL3834490 | 0.80 | EPHX1 (0.44) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL11132748 | 0.80 | SIGMAR1 (0.39) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL1397325 | 0.78 | EPHX1 (0.48) | EPHX1DPP4SIGMAR1TP53KDM4E | |
| SCHEMBL11301452 | 0.78 | EPHX1 (0.42) | EPHX1DPP4SIGMAR1TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | claimed |