Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493217 | 0.82 | PI4KA (0.54) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL16352519 | 0.82 | ESR1 (0.48) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL29386178 | 0.82 | ESR1 (0.48) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL22665831 | 0.80 | PI4KA (0.37) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL25585790 | 0.79 | ESR1 (0.48) | PI4KAPI4K2BPI4K2API4KBESR1 | |
| SCHEMBL31349388 | 0.78 | ADORA2B (0.46) | PI4KAPI4K2BPI4K2API4KBALDH1A1 | |
| SCHEMBL21155155 | 0.77 | ALDH1A1 (0.43) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL2631757 | 0.75 | MEN1 (0.48) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL28979811 | 0.75 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBDHFR | |
| SCHEMBL15796922 | 0.74 | ALDH1A1 (0.44) | PI4KAPI4K2BPI4K2API4KBDHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040491-A | Silicon-containing organic compound and application thereof, composition, adhesive film, preparation method and application thereof, photovoltaic module and preparation method thereof | 江苏绿人半导体有限公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-3512848-B1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
| WO-2018050583-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | CYCS, CYP3A4, CYP2E1 | PI4KA 1984/4885PI4K2B 2740/4885PI4K2A 2746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.