Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189085 | 0.93 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRCASP7KMT2A | |
| SCHEMBL465737 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRCASP7G6PD | |
| SCHEMBL31634613 | 0.88 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRCASP7G6PD | |
| SCHEMBL162974 | 0.86 | G6PD (0.61) | ALDH1A1HSD17B10CASP7G6PDCASP6 | |
| SCHEMBL31003730 | 0.86 | G6PD (0.61) | ALDH1A1HSD17B10CASP7G6PDCASP6 | |
| SCHEMBL2895994 | 0.80 | ALDH1A1 (0.67) | ALDH1A1HSD17B10CFTRCASP7KMT2A | |
| SCHEMBL25095928 | 0.78 | KDM4E (0.49) | ALDH1A1HSD17B10CFTRCASP7KMT2A | |
| SCHEMBL30217815 | 0.78 | KDM4E (0.49) | ALDH1A1HSD17B10CFTRCASP7KMT2A | |
| SCHEMBL28679016 | 0.78 | TSHR (0.50) | ALDH1A1HSD17B10CFTRKMT2AMAPT | |
| Methoxymethane SCHEMBL5903652 | 0.77 | G6PD (0.63) | ALDH1A1HSD17B10CFTRCASP7G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105934425-B | EBNA1 inhibitors and methods of use thereof | 威斯塔解剖学和生物学研究所 | 2020-08-07 | — | — | CN | disclosed |
| US-10421718-B2 | EBNA1 inhibitors and their method of use | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) | 2019-09-24 | — | — | US | disclosed |
| US-20180086699-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10421718-B2 | EBNA1 inhibitors and their method of use | EBNA1BP2, MLLT1, PML | ALDH1A1 3442/4885HSD17B10 3975/4885CFTR 2871/4885 |
| US-20180086699-A1 | EBNA1 INHIBITORS AND THEIR METHOD OF USE | EBNA1BP2, MLLT1, PML | ALDH1A1 3442/4885HSD17B10 3975/4885CFTR 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.