Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | CASP6 | P55212 | 1/20 | 0.61 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31003730 | 1.00 | G6PD (0.61) | G6PDCASP7CASP6PRNPMMP2 | |
| SCHEMBL19991850 | 0.86 | ALDH1A1 (0.50) | G6PDCASP7CASP6PRNPMMP2 | |
| SCHEMBL526919 | 0.84 | G6PD (0.74) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL161850 | 0.83 | METAP2 (0.47) | G6PDCASP7CASP6PRNPALDH1A1 | |
| SCHEMBL28281319 | 0.81 | G6PD (0.71) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL30806223 | 0.81 | G6PD (0.71) | G6PDCASP7CASP6MMP2ALDH1A1 | |
| SCHEMBL1188598 | 0.81 | G6PD (0.39) | G6PDCASP7CASP6PRNPALDH1A1 | |
| SCHEMBL28000603 | 0.81 | ALDH1A1 (0.42) | G6PDCASP7CASP6PRNPMMP2 | |
| SCHEMBL15626666 | 0.80 | MAPT (0.58) | ALDH1A1GLAMAPTGAAKMT2A | |
| SCHEMBL30453594 | 0.80 | MAPT (0.58) | ALDH1A1GLAMAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116482279-A | Method for detecting trace polyamine and polypeptide by bromine-labeled mass spectrometry | 西安培华学院 | 2023-07-25 | — | — | CN | claimed |
| CN-110330455-B | Amide derivative, preparation method and application thereof | 湖北省生物农药工程研究中心 | 2023-04-28 | — | — | CN | claimed |
| CN-109535010-A | A kind of preparation method of bromhexine hydrochloride | 广州品红制药有限公司 | 2019-03-29 | — | — | CN | claimed |
| CN-109111370-A | A kind of preparation method of the bromo- 2- aminobenzoic acid of 3,5- bis- | 浙江师范大学 | 2019-01-01 | — | — | CN | claimed |
| CN-109096135-A | A kind of preparation method of the bromo- 2- aminobenzoic acid of ambroxol hydrochloride intermediate 3,5- bis- | 浙江师范大学 | 2018-12-28 | — | — | CN | claimed |
| CN-108794409-A | The preparation method of thio -4 (1H) -one class compounds of -2,3- dihydroquinazolines of 2- | 联化科技股份有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-105461723-B | Phthalazines simultaneously assimilation compound of [1,2, b] quinazoline 8 and preparation method thereof and the application in antineoplastic | 广西师范大学 | 2017-12-08 | — | — | CN | claimed |
| CN-106975459-A | Modification cotton stem adsorbent for Adsorption pyrazinamide | 北京益净环保设备科技有限公司 | 2017-07-25 | — | — | CN | claimed |
| CN-106565684-A | 6-pyrromonazole substituted quinazoline compound, and derivative, synthetic method and application thereof | 南方医科大学 | 2017-04-19 | — | — | CN | claimed |
| CN-101768265-A | Modified nylon and preparation method thereof | UNIV SUZHOU | 2010-07-07 | — | — | CN | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| US-12637428-B2 | Isoquinoline derivatives as SIK2 inhibitors | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2026-05-26 | — | — | US | disclosed |
| US-20260102406-A1 | SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY | NEUPHARMA INC (US) | 2026-04-16 | — | — | US | disclosed |
| EP-3749325-B1 | DREADD ACTUATORS | US HEALTH (US) | 2026-04-08 | — | — | EP | disclosed |
| EP-4701783-A1 | PHOSPHINE-IMINO-QUINOLINE AND RELATED LIGANDS FOR USE IN ETHYLENE OLIGOMERIZATION PROCESSES | Chevron Phillips Chemical Company LP (US) | 2026-03-04 | — | — | EP | disclosed |
| WO-1999012908-A1 | QUINOLINE AND QUINAZOLINE DERIVATIVES HAVING CORTICOTROPIN RELEASING FACTOR (CRF) ANTAGONIST ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1999-03-18 | — | — | WO | disclosed |
| EP-0892797-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997030992-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-08-28 | — | — | WO | disclosed |
| US-5401745-A | Cardiovascular disorders or hypotensive agents | MERCK & CO., INC. (US) | 1995-03-28 | — | — | US | disclosed |
| WO-1994021259-A1 | QUINAZOLINONES SUBSTITUTED WITH PHENOXYPHENYLACETIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1994-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12637428-B2 | Isoquinoline derivatives as SIK2 inhibitors | SIK2, SIK1, SIK3 | G6PD 2495/4885CASP7 2710/4885CASP6 2439/4885 |
| US-20260102406-A1 | SUBSTITUTED QUINAZOLINES FOR INHIBITING KINASE ACTIVITY | BRAF, TTK, MAP4K2 | G6PD 3448/4885CASP7 880/4885CASP6 1945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.