Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 8/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993336 | 0.80 | — | — | |
| SCHEMBL19993380 | 0.79 | RXRA (0.40) | CYP17A1CYP11B1CYP11B2CYP19A1CYP3A4 | |
| SCHEMBL19373007 | 0.78 | POLB (0.42) | — | |
| SCHEMBL19373006 | 0.78 | POLB (0.42) | — | |
| SCHEMBL19993465 | 0.77 | — | — | |
| SCHEMBL19993403 | 0.74 | CYP17A1 (0.43) | ESR1ESR2CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL19993387 | 0.72 | TTR (0.44) | CYP11B1CYP11B2CYP19A1SAE1UBA2 | |
| SCHEMBL20093589 | 0.70 | LMNA (0.41) | HSD17B10 | |
| SCHEMBL20093629 | 0.70 | LMNA (0.41) | HSD17B10 | |
| SCHEMBL16848648 | 0.70 | LOXL2 (0.58) | CYP11B2CYP19A1SAE1UBA2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |