Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL627745 | 0.76 | TSHR (0.45) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL27573652 | 0.76 | TSHR (0.55) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL5655358 | 0.75 | ALDH1A1 (0.48) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL5655352 | 0.75 | ALDH1A1 (0.48) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL11747945 | 0.73 | RECQL (0.53) | TSHRALDH1A1AKR1C3SMN1; SMN2RECQL | |
| SCHEMBL11747951 | 0.73 | RECQL (0.53) | TSHRALDH1A1AKR1C3SMN1; SMN2RECQL | |
| SCHEMBL295401 | 0.73 | TSHR (0.50) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL5027068 | 0.73 | TSHR (0.50) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL295402 | 0.73 | TSHR (0.50) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 | |
| SCHEMBL598599 | 0.73 | TSHR (0.50) | TSHRALDH1A1AKR1C3SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200187500-A1 | PYRIDINE COMPOUNDS | BASF SE (DE) | 2020-06-18 | — | — | US | disclosed |
| EP-3606914-A1 | PYRIDINE COMPOUNDS | BASF SE (DE) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018184882-A1 | PYRIDINE COMPOUNDS | BASF SE (DE) | 2018-10-11 | — | — | WO | disclosed |
| WO-2018054711-A1 | PYRIDINE COMPOUNDS FOR CONTROLLING PHYTOPATHOGENIC HARMFUL FUNGI | BASF SE (DE) | 2018-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200187500-A1 | PYRIDINE COMPOUNDS | NQO1, NDUFS5, NDUFS4 | TSHR 4390/4885ALDH1A1 140/4885AKR1C3 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.