Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655358 | 1.00 | ALDH1A1 (0.48) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL4697791 | 0.80 | CYP2A6 (0.39) | ALDH1A1SMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL11048028 | 0.80 | CYP2A6 (0.39) | ALDH1A1SMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL4697789 | 0.80 | CYP2A6 (0.39) | ALDH1A1SMN1; SMN2RECQLNPC1RAB9A | |
| SCHEMBL5027068 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL598599 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL110774 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL295401 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL295402 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 | |
| SCHEMBL5078610 | 0.79 | TSHR (0.50) | ALDH1A1TSHRAKR1C3SMN1; SMN2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119639184-A | Polycrystalline alumina fiber high-temperature-resistant material and preparation method thereof | 扬州正茂制衣有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119639184-A | Polycrystalline alumina fiber high-temperature-resistant material and preparation method thereof | 扬州正茂制衣有限公司 | 2025-03-18 | — | — | CN | disclosed |
| US-7169786-B2 | Isoxazoline derivatives as anti-depressants | JANSSEN-CILAG S.A. (ES) | 2007-01-30 | — | — | US | disclosed |
| EP-1368358-B1 | ISOXAZOLINE DERIVATIVES AS ANTI-DEPRESSANTS | JANSSEN PHARMACEUTICA NV (BE) | 2006-08-23 | — | — | EP | disclosed |
| US-20040122037-A1 | Isoxazoline derivatives as anti-depressants | JANSSEN-CILAG S.A. (ES) | 2004-06-24 | — | — | US | disclosed |
| EP-1368358-A1 | ISOXAZOLINE DERIVATIVES AS ANTI-DEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002066484-A1 | ISOXAZOLINE DERIVATIVES AS ANTI-DEPRESSANTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-08-29 | — | — | WO | disclosed |
| US-5068325-A | Dopaminergic systems as hypotensives, sedatives, antitussives and/or antiphlogistics | KARL THOMAE GMBH (DE) | 1991-11-26 | — | — | US | disclosed |
| EP-0108627-A2 | Cephalosporin derivatives and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040122037-A1 | Isoxazoline derivatives as anti-depressants | HTR7, HTR1A, HTR2C | ALDH1A1 444/4885TSHR 224/4885AKR1C3 955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.