Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20290287 | 0.89 | POLB (0.51) | POLBALDH1A1KDM4EHPGDIDO1 | |
| SCHEMBL19626687 | 0.89 | SMN1; SMN2 (0.42) | POLBALDH1A1HPGDIDO1ALOX15 | |
| SCHEMBL22105260 | 0.84 | KMT2A (0.46) | POLBALDH1A1KDM4EHPGDIDO1 | |
| SCHEMBL21935695 | 0.83 | PORCN (0.46) | IDO1SMN1; SMN2 | |
| SCHEMBL19590966 | 0.83 | ALDH1A1 (0.51) | POLBALDH1A1KDM4EMAPK1MAPT | |
| SCHEMBL20029975 | 0.81 | MEN1 (0.48) | POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19626637 | 0.81 | PORCN (0.51) | — | |
| SCHEMBL22105261 | 0.81 | PSEN1 (0.41) | ALDH1A1KDM4EIDO1SMN1; SMN2MAPT | |
| SCHEMBL19626536 | 0.80 | MAPT (0.47) | ALDH1A1HPGDSMN1; SMN2MAPK1MAPT | |
| SCHEMBL19590909 | 0.79 | KMT2A (0.47) | ALDH1A1HPGDIDO1ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926320-B2 | Purine diones as Wnt pathway modulators | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2018-03-27 | — | — | US | disclosed |