Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20290287 | 0.85 | POLB (0.51) | ALDH1A1MAPTPOLBKDM4EGAA | |
| SCHEMBL20029975 | 0.84 | MEN1 (0.48) | ALDH1A1MAPTPOLBTHRBL3MBTL1 | |
| SCHEMBL19997366 | 0.83 | POLB (0.46) | ALDH1A1MAPTPOLBMAPK1KDM4E | |
| SCHEMBL19590972 | 0.82 | MEN1 (0.47) | ALDH1A1MAPTPOLBTHRBKDM4E | |
| SCHEMBL22105260 | 0.79 | KMT2A (0.46) | ALDH1A1MAPTPOLBMAPK1KDM4E | |
| SCHEMBL19590909 | 0.78 | KMT2A (0.47) | ALDH1A1MAPTL3MBTL1GAAKMT2A | |
| SCHEMBL21935695 | 0.78 | PORCN (0.46) | TP53 | |
| SCHEMBL19590905 | 0.78 | TRPA1 (0.41) | ALDH1A1MAPTPOLBGAAKMT2A | |
| SCHEMBL19590937 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBGAAKMT2A | |
| SCHEMBL20030198 | 0.76 | TRPA1 (0.56) | ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815838-B2 | Methods and compositions for treating pain | HYDRA BIOSCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |