Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000474 | 0.96 | L3MBTL1 (0.47) | PARP10ACACBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3038638 | 0.94 | ALDH1A1 (0.50) | ACACBALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL9022349 | 0.86 | HRH1 (0.56) | ALDH1A1L3MBTL1KDM4EMEN1NPC1 | |
| SCHEMBL8259263 | 0.86 | ADRB1 (0.57) | ACACBALDH1A1KDM4EHRH3HRH1 | |
| SCHEMBL9014013 | 0.84 | HRH1 (0.54) | ALDH1A1L3MBTL1KDM4EMEN1NPC1 | |
| SCHEMBL18553743 | 0.81 | ADRB1 (0.56) | ACACBHRH3HRH1 | |
| SCHEMBL11218856 | 0.81 | MEN1 (0.43) | ACACBALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL11218853 | 0.81 | MEN1 (0.43) | ACACBALDH1A1L3MBTL1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6539081 | 0.80 | ADRB1 (0.54) | ACACBHRH3HRH1 | |
| SCHEMBL16393823 | 0.80 | ACACB (0.51) | ACACBALDH1A1L3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997024-B1 | PYRROLIDINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2018-03-28 | — | — | EP | disclosed |