Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20000617 | 0.74 | ACACB (0.48) | ACACBGPR119HRH3 | |
| SCHEMBL30932113 | 0.74 | ACACB (0.48) | ACACBGPR119CHRM4HRH3 | |
| SCHEMBL23057533 | 0.69 | ACACB (0.49) | ACACBGPR119 | |
| SCHEMBL19041966 | 0.69 | CLK2 (0.46) | ACACBGPR119HRH3 | |
| SCHEMBL12949399 | 0.67 | CHRM4 (0.49) | PDGFRBPDGFRAABL1CHRM4 | |
| SCHEMBL4021756 | 0.67 | MCHR1 (0.45) | ACACBPDGFRBPDGFRAABL1HPGD | |
| SCHEMBL2581459 | 0.67 | CHRNA3 (0.48) | PDGFRBPDGFRAABL1CHRM4 | |
| SCHEMBL16691251 | 0.67 | CHRNB2 (0.46) | ACACBPDGFRBPDGFRAABL1HPGD | |
| SCHEMBL2580914 | 0.67 | CHRNA3 (0.48) | PDGFRBPDGFRAABL1CHRM4 | |
| SCHEMBL2586308 | 0.67 | LOX (0.47) | ACACBGRM2PDGFRBPDGFRAABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679487-A | 4- (5- (cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-dione and preparation method and application thereof | 张淑华 | 2021-04-20 | — | — | CN | claimed |
| CN-112679487-A | 4- (5- (cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-dione and preparation method and application thereof | 张淑华 | 2021-04-20 | — | — | CN | disclosed |
| CN-112679487-A | 4- (5- (cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-dione and preparation method and application thereof | 张淑华 | 2021-04-20 | — | — | CN | disclosed |
| CN-112679487-A | 4- (5- (cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-dione and preparation method and application thereof | 张淑华 | 2021-04-20 | — | — | CN | disclosed |