Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21675613 | 0.84 | RAB9A (0.50) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL14243062 | 0.81 | CHRNB2 (0.54) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL1692767 | 0.81 | RAB9A (0.45) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL19308678 | 0.80 | HDAC2 (0.44) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL2229068 | 0.80 | RAB9A (0.44) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL5568829 | 0.79 | RAB9A (0.43) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL1692721 | 0.79 | RAB9A (0.43) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL15703162 | 0.79 | RAB9A (0.43) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL21417415 | 0.77 | RAB9A (0.42) | RAB9ATSHRMEN1HPGDKMT2A | |
| SCHEMBL20364801 | 0.77 | HDAC2 (0.43) | RAB9ATSHRMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |