Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4550247 | 0.83 | L3MBTL3 (0.58) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL23173215 | 0.82 | MCHR1 (0.41) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL14997483 | 0.81 | EPHX2 (0.43) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL19710577 | 0.81 | KDM4E (0.45) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL14344778 | 0.80 | ALDH1A1 (0.43) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL13803962 | 0.79 | NPY5R (0.47) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL220870 | 0.79 | EPHX2 (0.42) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL24029432 | 0.79 | LTA4H (0.41) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL7269265 | 0.78 | NPY5R (0.49) | EPHX2EPHX1L3MBTL3CYP1A2TDP1 | |
| SCHEMBL18215059 | 0.77 | ALDH1A1 (0.36) | EPHX2EPHX1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |