Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | APOL1 | O14791 | 1/20 | 0.37 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002250 | 0.86 | MAPT (0.48) | MEN1KMT2AALDH1A1RORCGRM3 | |
| SCHEMBL20002341 | 0.86 | MAPT (0.48) | MEN1KMT2AALDH1A1RORCGRM3 | |
| SCHEMBL20002969 | 0.82 | NOTUM (0.45) | KMT2AALDH1A1SMN1; SMN2RORCRAB9A | |
| SCHEMBL20002958 | 0.82 | NOTUM (0.48) | KMT2AALDH1A1SMN1; SMN2RORCMAPT | |
| SCHEMBL20002167 | 0.82 | KDM1A (0.40) | ALDH1A1SMN1; SMN2RORCNPC1RAB9A | |
| SCHEMBL20003049 | 0.82 | AKR1C3 (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL20002957 | 0.82 | NOTUM (0.48) | KMT2AALDH1A1SMN1; SMN2RORCMAPT | |
| SCHEMBL20002280 | 0.82 | TACR1 (0.40) | RORC | |
| SCHEMBL20002669 | 0.82 | NOTUM (0.45) | KMT2AALDH1A1SMN1; SMN2RORCRAB9A | |
| SCHEMBL20002664 | 0.81 | TSHR (0.41) | KMT2ASMN1; SMN2NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |