Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 13/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20002737 | 0.90 | SLC22A12 (0.33) | — | |
| SCHEMBL18799682 | 0.90 | RORC (0.40) | RORCNR1I2 | |
| SCHEMBL16886235 | 0.84 | ACHE (0.34) | ACHERORCEEDPKMNR1I2 | |
| SCHEMBL16886260 | 0.83 | RORC (0.39) | RORCNR1I2 | |
| SCHEMBL20002812 | 0.82 | TAAR1 (0.46) | KMT2A | |
| SCHEMBL20002194 | 0.81 | KDM1A (0.39) | RORCKMT2A | |
| SCHEMBL20002758 | 0.80 | RORC (0.36) | RORC | |
| SCHEMBL20001981 | 0.78 | RORC (0.37) | RORCNR1I2 | |
| SCHEMBL18214991 | 0.75 | RORC (0.40) | RORCNR1I2 | |
| SCHEMBL13248032 | 0.74 | ACHE (0.44) | ACHEEEDPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |