Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.39 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422675 | 0.83 | EPHX2 (0.42) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL3833697 | 0.83 | SLC6A1 (0.42) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL14366337 | 0.82 | CPN1 (0.51) | ITGB3ITGA2B | |
| SCHEMBL17275234 | 0.79 | ALDH1A1 (0.43) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL6179700 | 0.79 | ITGB3 (0.45) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL18123287 | 0.78 | SLC6A1 (0.42) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL16887542 | 0.76 | ALDH1A1 (0.39) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL28955984 | 0.76 | ALDH1A1 (0.39) | ITGB3ITGA2BSLC6A1GABRA5GABRB2 | |
| SCHEMBL1787747 | 0.76 | EPHX2 (0.47) | ITGB3ITGA2B | |
| SCHEMBL7876014 | 0.76 | TPSAB1 (0.52) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092229-B1 | PYRROLIDINYL SULFONE DERIVATIVES AND THEIR USE AS ROR GAMMA MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-28 | — | — | EP | disclosed |