Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 5/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.30 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.30 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235888 | 0.86 | DNM1 (0.58) | ALDH1A1TSHRDNM1 | |
| SCHEMBL19786168 | 0.83 | SLC6A4 (0.32) | — | |
| SCHEMBL23457621 | 0.79 | DNM1 (0.48) | ALDH1A1TSHRDNM1 | |
| Bromide SCHEMBL19741466 | 0.79 | DNM1 (0.38) | ALDH1A1TSHRDNM1 | |
| SCHEMBL28268989 | 0.79 | LMNA (0.39) | TSHRDNM1 | |
| SCHEMBL10491044 | 0.79 | LMNA (0.39) | TSHRDNM1 | |
| SCHEMBL23686853 | 0.79 | LMNA (0.39) | TSHRDNM1 | |
| Hydrochloric Acid SCHEMBL29482100 | 0.77 | LMNA (0.38) | TSHRDNM1 | |
| SCHEMBL26511932 | 0.76 | OPRM1 (0.39) | ALDH1A1TSHRDNM1 | |
| SCHEMBL27818797 | 0.76 | OPRM1 (0.39) | ALDH1A1TSHRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018057834-A1 | COMBINATORY TREATMENT STRATEGIES OF CANCER BASED ON RNA POLYMERASE I INHIBITION | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-03-29 | — | — | WO | disclosed |