Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23457621 | 0.81 | DNM1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL20003252 | 0.79 | ALDH1A1 (0.44) | DNM1ALDH1A1TSHR | |
| SCHEMBL13976195 | 0.74 | DNM1 (0.52) | DNM1ALDH1A1TSHR | |
| SCHEMBL18221733 | 0.74 | DNM1 (0.52) | DNM1ALDH1A1TSHR | |
| SCHEMBL27800763 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL11699658 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL9204346 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL9541689 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL24353239 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR | |
| SCHEMBL14625028 | 0.73 | EPHX1 (0.48) | DNM1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025070397-A1 | ETHYLENE GLYCOL, POLYESTER, POLYESTER PELLETS, MOLDED ARTICLE, FILM, FIBERS, FIBER ARTICLE, MOLDED ARTICLE, PREFORM, POLYESTER FILM, LAMINATED FILM, LAMINATE, AND PACKAGE | 大日本印刷株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-10308574-B2 | Reduction catalyst and chemical reactor | KABUSHIKI KAISHA TOSHIBA (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170369405-A1 | REDUCTION CATALYST AND CHEMICAL REACTOR | KABUSHIKI KAISHA TOSHIBA (JP) | 2017-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308574-B2 | Reduction catalyst and chemical reactor | MPO, NOX4, IDH2 | DNM1 1160/4885ALDH1A1 796/4885TSHR 3892/4885 |
| US-20170369405-A1 | REDUCTION CATALYST AND CHEMICAL REACTOR | MPO, NOX4, IDH2 | DNM1 1160/4885ALDH1A1 796/4885TSHR 3892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.