Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.40 |
| ▸ | AXL | P30530 | 9/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20003621 | 0.87 | MET (0.49) | METAXLKDR | |
| SCHEMBL22643607 | 0.79 | HTR1A (0.42) | METAXLKDR | |
| SCHEMBL20003725 | 0.72 | MET (0.55) | METAXLKDR | |
| SCHEMBL20003634 | 0.71 | FGFR2 (0.47) | METAXLKDR | |
| SCHEMBL23617110 | 0.67 | FGFR2 (0.67) | METAXLKDR | |
| SCHEMBL19373324 | 0.67 | FGFR2 (0.47) | METAXLKDR | |
| SCHEMBL29822421 | 0.67 | FGFR2 (0.67) | METAXLKDR | |
| SCHEMBL22521192 | 0.66 | FGFR2 (0.59) | METAXLKDR | |
| SCHEMBL22643706 | 0.66 | MET (0.57) | METAXLKDR | |
| SCHEMBL10269247 | 0.66 | MET (0.54) | METAXLKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299369-A1 | PYRIDO-AZAHETERECYDIC COMPOUND AND PREPARATION METHOD AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2018-03-28 | — | — | EP | disclosed |