Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005391 | 0.94 | F2RL3 (0.37) | FAAHF2RL3 | |
| SCHEMBL2002866 | 0.93 | FAAH (0.41) | FAAH | |
| SCHEMBL2007302 | 0.91 | FAAH (0.43) | FAAHPLA2G2ACES1 | |
| SCHEMBL2010346 | 0.91 | PLA2G2A (0.37) | FAAHPLA2G2AF2RL3 | |
| SCHEMBL2003039 | 0.91 | FAAH (0.38) | FAAH | |
| SCHEMBL2004514 | 0.91 | F2RL3 (0.39) | FAAHPLA2G2AF2RL3 | |
| SCHEMBL2003840 | 0.90 | FAAH (0.40) | FAAHCES1 | |
| SCHEMBL2008038 | 0.90 | FAAH (0.39) | FAAH | |
| SCHEMBL2003836 | 0.90 | FAAH (0.41) | FAAH | |
| SCHEMBL2003372 | 0.89 | PLA2G2A (0.38) | PLA2G2AF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960544-B2 | Useful indole compounds | IRONWOOD PHARMACEUTICALS, INC. (US) | 2011-06-14 | — | — | US | disclosed |