Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CYBB | P04839 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL194538 | 0.94 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1TSHRSLC9A5NOX1 | |
| Hydrochloric Acid SCHEMBL29018536 | 0.92 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1TSHRSLC9A5NOX1 | |
| SCHEMBL18538525 | 0.86 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1TSHRSLC9A5CNR1 | |
| SCHEMBL19823015 | 0.83 | MMP14 (0.43) | L3MBTL1ALDH1A1TSHRNOX1KDM4E | |
| SCHEMBL22537499 | 0.83 | MMP13 (0.44) | L3MBTL1ALDH1A1TSHRTDP1HSD17B1 | |
| SCHEMBL22537676 | 0.82 | L3MBTL1 (0.43) | L3MBTL1NOX1RAB9APOLBCYBB | |
| SCHEMBL22537682 | 0.82 | ALDH1A1 (0.44) | ALDH1A1TSHRCNR1MAPTMCOLN3 | |
| SCHEMBL6449723 | 0.82 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1TSHRCNR1KDM4E | |
| SCHEMBL20004343 | 0.80 | APP (0.49) | ALDH1A1TSHRMAPTMCOLN3 | |
| SCHEMBL14303779 | 0.80 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1TSHRCNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |