Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849628 | 0.89 | L3MBTL1 (0.45) | SMN1; SMN2L3MBTL1TSHRSLC9A5 | |
| SCHEMBL22537487 | 0.83 | L3MBTL1 (0.51) | SMN1; SMN2L3MBTL1LTA4HTSHRHSD17B10 | |
| SCHEMBL22537499 | 0.83 | MMP13 (0.44) | SMN1; SMN2L3MBTL1TSHRMMP2MMP9 | |
| SCHEMBL20005167 | 0.79 | MAPT (0.41) | SMN1; SMN2L3MBTL1TSHRMEN1KMT2A | |
| SCHEMBL20004348 | 0.79 | L3MBTL1 (0.48) | SMN1; SMN2L3MBTL1MEN1KMT2AMMP2 | |
| SCHEMBL15466179 | 0.77 | RPS6KA2 (0.45) | SMN1; SMN2L3MBTL1TSHRMEN1KMT2A | |
| 1,4-Butanediol SCHEMBL4599328 | 0.76 | LTA4H (0.47) | SMN1; SMN2LTA4HCYP2C19NPC1RAB9A | |
| SCHEMBL11343713 | 0.76 | ALDH1A1 (0.54) | L3MBTL1LTA4HTSHRMEN1KMT2A | |
| SCHEMBL8925998 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2LTA4HCYP2C19NPC1RAB9A | |
| SCHEMBL475215 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2LTA4HCYP2C19NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |