Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.39 |
| ▸ | SNCA | P37840 | 9/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20005146 | 0.85 | SNCA (0.36) | SNCAMAPT | |
| SCHEMBL21147267 | 0.83 | SNCA (0.51) | APPSNCAMAPT | |
| SCHEMBL20004453 | 0.83 | SNCA (0.36) | SNCAMAPT | |
| SCHEMBL21147086 | 0.77 | GRM5 (0.41) | SNCAMAPT | |
| SCHEMBL20004515 | 0.76 | APP (0.38) | APPSNCAMAPT | |
| SCHEMBL20004527 | 0.76 | SNCA (0.37) | SNCAMAPT | |
| SCHEMBL22537542 | 0.76 | SNCA (0.39) | SNCAMAPT | |
| SCHEMBL21147289 | 0.74 | PIK3CA (0.38) | — | |
| SCHEMBL20005013 | 0.74 | GRM5 (0.40) | — | |
| SCHEMBL22537754 | 0.74 | SNCA (0.52) | APPSNCAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515912-B1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NAT RECH SCIENT (FR) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |