Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19999591 | 0.93 | RAB9A (0.42) | SMN1; SMN2RAB9ANPC1TP53PKM | |
| SCHEMBL20004586 | 0.89 | GRM5 (0.37) | AURKAABL1NTRK1LCKCSF1R | |
| SCHEMBL19999454 | 0.82 | FFAR1 (0.43) | HSD17B10FFAR1 | |
| SCHEMBL20006883 | 0.81 | FFAR1 (0.42) | HSD17B10FFAR1 | |
| SCHEMBL20004878 | 0.81 | HRH3 (0.38) | HSD17B10FFAR1 | |
| SCHEMBL20005267 | 0.81 | RARA (0.39) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL20004894 | 0.81 | RARA (0.39) | SMN1; SMN2RAB9ANPC1MAPTL3MBTL1 | |
| SCHEMBL20005228 | 0.80 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL20005285 | 0.80 | FFAR1 (0.40) | SMN1; SMN2RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL19999457 | 0.79 | HRH3 (0.38) | HSD17B10FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |