SCHEMBL20004797

SCHEMBL20004797

CCCCOc1cc(F)c(C#Cc2ccc(-c3ccc(-c4ccc(-c5ccc(C)cc5F)cc4F)cc3F)cc2)c(CC)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 2/20 0.37
S1PR3 Q99500 2/20 0.37
RARA P10276 1/20 0.37
RARB P10826 1/20 0.37
MCL1 Q07820 1/20 0.36
FFAR1 O14842 2/20 0.35
FFAR4 Q5NUL3 1/20 0.35
CYP2C9 P11712 4/20 0.34
MOGAT2 Q3SYC2 4/20 0.34
ACACB O00763 2/20 0.33
ACACA Q13085 1/20 0.33
PPARD Q03181 1/20 0.33
GRM5 P41594 1/20 0.33
MAOB P27338 1/20 0.33
PTPN11 Q06124 1/20 0.33
HMOX1 P09601 1/20 0.33
PLK1 P53350 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20004614 0.94 RARB (0.41) S1PR1S1PR3RARARARBMCL1
SCHEMBL20004683 0.87 ACACB (0.39) S1PR1S1PR3RARBFFAR1FFAR4
SCHEMBL19999622 0.86 RARA (0.38) RARARARBFFAR1FFAR4ACACB
SCHEMBL20004754 0.83 ACACB (0.40) RARARARBACACB
SCHEMBL20005209 0.81 MCHR1 (0.36) RARARARBACACBACACAGRM5
SCHEMBL20005281 0.81 RARA (0.40) RARARARBACACBACACAMAOB
SCHEMBL19999526 0.79 RARB (0.45) S1PR1S1PR3RARARARBFFAR1
SCHEMBL20004768 0.79 RARB (0.45) RARARARBMCL1FFAR1FFAR4
SCHEMBL19999429 0.78 RARB (0.43) S1PR1S1PR3RARARARBFFAR1
SCHEMBL20005218 0.78 RARA (0.36) S1PR1S1PR3RARARARBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3299439-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC Corporation (JP) 2018-03-28 EP disclosed