Methylamine

Methylamine

SCHEMBL200049

CCCC(C)(C)O[SiH3].CN

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459257 0.94
Ethylenediamine SCHEMBL5701197 0.90 LMNA (0.30) LMNAHSD17B10
Ethylene Glycol SCHEMBL8389322 0.84 CYP4F2 (0.31) LMNAHSD17B10
SCHEMBL3844495 0.79
SCHEMBL2058636 0.78 TSHR (0.37)
SCHEMBL692449 0.78
Ethylamine SCHEMBL2799213 0.77 FDPS (0.35)
SCHEMBL6037308 0.76 TSHR (0.42)
SCHEMBL6037294 0.76 TSHR (0.42)
SCHEMBL9016161 0.76 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2142558-B1 HYDROLYZABLE SILANES OF LOW VOC-GENERATING POTENTIAL AND RESINOUS COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-10-05 EP disclosed
EP-2137198-B1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-05-18 EP disclosed
EP-2160424-B1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE MOMENTIVE PERFORMANCE MAT INC (US) 2015-03-04 EP disclosed
US-8088940-B2 Having an organofunctional group bonded to a silicon atom through a stable bridging group that is able to react with an organic resin (2,2,4,4,6-pentamethyl-[1,3,2]dioxasilinane); enhanced storage stability, adhesion strength, durability, filler dispersibility, tensile strength, elongation, tear strength MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-01-03 US disclosed
US-7989651-B2 trimethoxysilylpropyl-carbamic acid oxiranylmethyl ester; reacting glycidol with gamma-isocyanatopropyltriethoxysilane in presence of dibutyltin laurate catalyst MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2011-08-02 US disclosed
EP-2160424-A1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE Momentive Performance Materials Inc. (US) 2010-03-10 EP disclosed
EP-2137198-A1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME Momentive Performance Materials Inc. (US) 2009-12-30 EP disclosed
US-7569645-B2 Curable silyl-containing polymer composition containing paint adhesion additive MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-08-04 US disclosed
WO-2009005642-A1 CURABLE SILYL-CONTAINING POLYMER COMPOSITION CONTAINING PAINT ADHESION ADDITIVE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-01-08 WO disclosed
US-20090005498-A1 Curable silyl-containing polymer composition containing paint adhesion additive MOMENTIVE PERFORMANCE MATERIALS INC. 2009-01-01 US disclosed
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-10-02 US disclosed
WO-2008112150-A1 EPOXYSILANES, PROCESSES FOR THEIR MANUFACTURE AND CURABLE COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-09-18 WO disclosed
US-20080221238-A1 Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2008-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080237537-A1 Hydrolyzable silanes of low VOC-generating potential and resinous compositions containing same GSTM1, GSTP1, GSTM2 LMNA 3705/4885HSD17B10 577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.