Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16669437 | 0.85 | L3MBTL3 (0.44) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL28627355 | 0.83 | L3MBTL1 (0.42) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL10182603 | 0.83 | HRH3 (0.46) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL31341874 | 0.83 | L3MBTL3 (0.45) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL31252540 | 0.81 | AKR1C3 (0.57) | AKR1C3SLC6A2SLC6A4MAPTIGF1R | |
| SCHEMBL21590235 | 0.81 | USP2 (0.58) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL578424 | 0.81 | ALDH1A1 (0.50) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL25042402 | 0.80 | L3MBTL3 (0.40) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL19462640 | 0.79 | TSHR (0.40) | AKR1C3L3MBTL3L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL22537505 | 0.78 | ADRB1 (0.55) | AKR1C3L3MBTL3L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018055316-A1 | COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-29 | — | — | WO | disclosed |