Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004879 | 0.91 | FFAR1 (0.34) | ESR1ESR2FFAR1CYP11B1CYP11B2 | |
| SCHEMBL20005240 | 0.85 | FFAR1 (0.33) | FFAR1AKR1C3AKR1C2KDM1APDE3B | |
| SCHEMBL20005213 | 0.85 | FFAR1 (0.33) | FFAR1AKR1C3AKR1C2KDM1APDE3B | |
| SCHEMBL20006703 | 0.85 | PDE3B (0.33) | FFAR1AKR1C3AKR1C2CYP11B1CYP11B2 | |
| SCHEMBL20006719 | 0.85 | PDE3B (0.33) | FFAR1AKR1C3AKR1C2CYP11B1CYP11B2 | |
| SCHEMBL20005231 | 0.84 | FFAR1 (0.34) | FFAR1KDM1APDE3BPDE3A | |
| SCHEMBL20004586 | 0.83 | GRM5 (0.37) | CYP11B1CYP11B2GRM5AAK1 | |
| SCHEMBL20004894 | 0.83 | RARA (0.39) | FFAR1 | |
| SCHEMBL20005267 | 0.83 | RARA (0.39) | FFAR1 | |
| SCHEMBL20005285 | 0.82 | FFAR1 (0.40) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299439-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC Corporation (JP) | 2018-03-28 | — | — | EP | disclosed |