Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20004631 | 0.86 | AAK1 (0.39) | AAK1ARALDH1A1ACHEGRM5 | |
| SCHEMBL28034740 | 0.84 | AAK1 (0.45) | AAK1ARALDH1A1ACHEGRM5 | |
| SCHEMBL9512484 | 0.80 | AAK1 (0.44) | AAK1ARPDGFRBPDGFRAKDM4E | |
| SCHEMBL19999406 | 0.79 | TSHR (0.47) | ALDH1A1MAPT | |
| SCHEMBL9512234 | 0.79 | GRM5 (0.45) | ALDH1A1GRM5CA12CA2CA9 | |
| SCHEMBL19999416 | 0.78 | ACACB (0.45) | AAK1 | |
| SCHEMBL31442895 | 0.77 | ACHE (0.50) | AAK1ARALDH1A1ACHEGRM5 | |
| SCHEMBL91913 | 0.76 | AAK1 (0.43) | AAK1ARALDH1A1ACHEGRM5 | |
| SCHEMBL8979151 | 0.76 | GRM5 (0.45) | ALDH1A1ACHEGRM5CA12CA2 | |
| SCHEMBL12011040 | 0.76 | CYP11B1 (0.43) | AAK1ARMAPTGRM5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10208249-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2019-02-19 | — | — | US | disclosed |
| US-20180086979-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-03-29 | — | — | US | disclosed |