Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680627 | 0.90 | ACHE (0.47) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL27425161 | 0.88 | ACHE (0.45) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL26157383 | 0.83 | ACHE (0.55) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL23484704 | 0.83 | ACHE (0.55) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL22875430 | 0.82 | ACHE (0.59) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL17108656 | 0.82 | ACHE (0.53) | ACHECHRM5ADRA2COPRD1OPRK1 | |
| SCHEMBL14708016 | 0.82 | OPRL1 (0.40) | ACHEOPRD1OPRK1OPRL1 | |
| SCHEMBL10216738 | 0.82 | OPRL1 (0.40) | ACHEOPRD1OPRK1OPRL1 | |
| SCHEMBL10216732 | 0.82 | OPRL1 (0.40) | ACHEOPRD1OPRK1OPRL1 | |
| SCHEMBL21947721 | 0.81 | ACHE (0.40) | ACHECHRM5ADRA2COPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180086736-A1 | RORC2 INHIBITORS AND METHODS OF USE THEREOF | PFIZER INC. (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086736-A1 | RORC2 INHIBITORS AND METHODS OF USE THEREOF | RORC, RORB, RORA | ACHE 4376/4885SHBG 722/4885CHRM5 3440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.