SCHEMBL20008194

SCHEMBL20008194

CNc1ccc(S(=O)(=O)C(=O)OCc2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
LMNA P02545 2/20 0.45
CA1 P00915 4/20 0.44
CA2 P00918 4/20 0.44
CA12 O43570 3/20 0.44
CA9 Q16790 3/20 0.44
KMT2A Q03164 2/20 0.43
GAA P10253 1/20 0.43
RAB9A P51151 1/20 0.43
NAMPT P43490 1/20 0.43
MAPT P10636 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
TGM2 P21980 2/20 0.42
F13A1 P00488 1/20 0.42
TGM1 P22735 1/20 0.42
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20008190 0.85 RAB9A (0.45) ALDH1A1LMNACA1CA2CA12
SCHEMBL3392315 0.84 LMNA (0.62) ALDH1A1LMNACA1CA2CA12
SCHEMBL19824655 0.80 ALDH1A1 (0.49) ALDH1A1LMNACA1CA2CA12
SCHEMBL20008189 0.78 LMNA (0.39) ALDH1A1LMNACA1CA2CA12
SCHEMBL22702705 0.77 AR (0.50) ALDH1A1CA1CA2CA12CA9
SCHEMBL27562443 0.76 POLB (0.68) ALDH1A1KMT2AGAARAB9ANAMPT
SCHEMBL6425991 0.76 KMT2A (0.69) ALDH1A1LMNACA1CA2KMT2A
SCHEMBL26812910 0.75 ALDH1A1 (0.55) ALDH1A1LMNACA1CA2CA12
SCHEMBL20008087 0.75 RAB9A (0.46) ALDH1A1LMNACA1CA2CA12
SCHEMBL20009200 0.75 RAB9A (0.43) ALDH1A1LMNACA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086918-A1 MIXTURES OF REACTIVE DYES AND THEIR USE FOR THE DYING OR PRINTING FIBRE MATERIALS HUNTSMAN INTERNATIONAL LLC 2018-03-29 US disclosed