SCHEMBL20008190

SCHEMBL20008190

CNc1cccc(S(=O)(=O)C(=O)OCc2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.45
MGLL Q99685 1/20 0.45
CA12 O43570 5/20 0.45
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45
CA9 Q16790 5/20 0.45
F13A1 P00488 1/20 0.43
TGM2 P21980 1/20 0.43
TGM1 P22735 1/20 0.43
TGM3 Q08188 1/20 0.43
ALDH1A1 P00352 1/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
LMNA P02545 1/20 0.41
ENPP2 Q13822 1/20 0.41
CACNA1H O95180 1/20 0.41
HTR6 P50406 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009200 0.87 RAB9A (0.43) RAB9AMGLLCA12CA1CA2
SCHEMBL20008194 0.85 ALDH1A1 (0.46) RAB9ACA12CA1CA2CA9
SCHEMBL20008087 0.83 RAB9A (0.46) RAB9AMGLLCA12CA1CA2
SCHEMBL23026138 0.80 MAOB (0.55) RAB9AALDH1A1KMT2AMEN1LMNA
SCHEMBL20008189 0.78 LMNA (0.39) RAB9ACA12CA1CA2CA9
SCHEMBL20008188 0.76 ALDH1A1 (0.41) CA12CA1CA2CA9ALDH1A1
SCHEMBL15648038 0.75 MGLL (0.72) RAB9AMGLLALDH1A1LMNAENPP2
SCHEMBL3392315 0.75 LMNA (0.62) CA12CA1CA2CA9ALDH1A1
SCHEMBL26812910 0.72 ALDH1A1 (0.55) RAB9ACA12CA1CA2CA9
SCHEMBL19824655 0.71 ALDH1A1 (0.49) RAB9ACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086918-A1 MIXTURES OF REACTIVE DYES AND THEIR USE FOR THE DYING OR PRINTING FIBRE MATERIALS HUNTSMAN INTERNATIONAL LLC 2018-03-29 US disclosed