Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145298 | 0.86 | — | — | |
| SCHEMBL23463737 | 0.86 | — | — | |
| SCHEMBL21431099 | 0.81 | DNM1 (0.35) | ALDH1A1TDP1CA2CA1TSHR | |
| SCHEMBL23901850 | 0.81 | DNM1 (0.35) | ALDH1A1TDP1CA2CA1TSHR | |
| SCHEMBL17974411 | 0.79 | DNM1 (0.33) | ALDH1A1TDP1DNM1OPRM1 | |
| SCHEMBL24703744 | 0.78 | — | — | |
| SCHEMBL26399662 | 0.78 | — | — | |
| SCHEMBL27614168 | 0.75 | CA2 (0.32) | CA2CA1MAPK1 | |
| SCHEMBL23901837 | 0.74 | OPRM1 (0.42) | CA1TSHRDNM1OPRM1 | |
| SCHEMBL10442026 | 0.73 | ALDH1A1 (0.33) | ALDH1A1CA2CA1DNM1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |