Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009463 | 0.65 | NPC1 (0.32) | — | |
| SCHEMBL20008581 | 0.61 | TP53 (0.39) | — | |
| SCHEMBL20264639 | 0.56 | RAF1 (0.49) | RAF1 | |
| SCHEMBL28642930 | 0.56 | HPGD (0.52) | — | |
| SCHEMBL20008254 | 0.55 | NPC1 (0.34) | — | |
| SCHEMBL13283345 | 0.54 | HTR2C (0.56) | — | |
| SCHEMBL21416684 | 0.53 | ACMSD (0.34) | — | |
| SCHEMBL14433081 | 0.52 | — | — | |
| SCHEMBL17027850 | 0.52 | MAP4K4 (0.55) | RAF1 | |
| SCHEMBL21312221 | 0.52 | MGLL (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |