Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008300 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2SLC9A1RAB9ALCKTSHR | |
| SCHEMBL16848667 | 0.68 | SLC9A1 (0.45) | SMN1; SMN2SLC9A1RAB9AALOX15CREBBP | |
| SCHEMBL20008350 | 0.65 | — | — | |
| SCHEMBL20008772 | 0.65 | BRAF (0.31) | — | |
| SCHEMBL21041662 | 0.64 | RAB9A (0.37) | SMN1; SMN2SLC9A1RAB9ATSHRNPC1 | |
| SCHEMBL21041668 | 0.64 | SLC9A1 (0.35) | SMN1; SMN2SLC9A1RAB9ATSHRNPC1 | |
| SCHEMBL19782622 | 0.64 | RAB9A (0.46) | SMN1; SMN2SLC9A1RAB9ATSHRNPC1 | |
| SCHEMBL20008148 | 0.63 | CRHR1 (0.32) | — | |
| SCHEMBL14685487 | 0.62 | RAB9A (0.45) | SMN1; SMN2SLC9A1RAB9ATSHRPOLB | |
| SCHEMBL19733923 | 0.62 | SMN1; SMN2 (0.46) | SMN1; SMN2SLC9A1RAB9ATSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |