Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24806246 | 1.00 | GABRA1 (0.47) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL19485771 | 0.89 | HTR2A (0.42) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL22536330 | 0.89 | HTR2A (0.42) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL21297470 | 0.84 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL13532277 | 0.81 | MEN1 (0.39) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL22536331 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL19485809 | 0.80 | HTR2A (0.49) | GABRA1GABRB2MAPTHTR2AMAPK1 | |
| SCHEMBL19492401 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL19346233 | 0.78 | GABRA1 (0.43) | GABRA1GABRB2MEN1KMT2APOLB | |
| SCHEMBL13343333 | 0.77 | MEN1 (0.39) | GABRA1GABRB2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317213-A1 | Anti-CD3 Antibody Folate Bioconjugates and Their Uses | AMBRX, INC. (US) | 2021-10-14 | — | — | US | disclosed |
| US-10800856-B2 | Prostate-specific membrane antigen antibody drug conjugates | AMBRX, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10710065-B2 | Polymeric materials for electrochemical cells and ion separation processes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-07-14 | — | — | US | disclosed |
| US-20180085744-A1 | POLYMERIC MATERIALS FOR ELECTROCHEMICAL CELLS AND ION SEPARATION PROCESSES | UNITED STATES DEPARTMENT OF ENERGY | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317213-A1 | Anti-CD3 Antibody Folate Bioconjugates and Their Uses | FOLR2, FOLR1, CD2 | GABRA1 680/4885GABRB2 762/4885MEN1 2830/4885 |
| US-20180085744-A1 | POLYMERIC MATERIALS FOR ELECTROCHEMICAL CELLS AND ION SEPARATION PROCESSES | ALG1, MLEC, MSN | GABRA1 3823/4885GABRB2 4006/4885MEN1 939/4885 |
| US-10800856-B2 | Prostate-specific membrane antigen antibody drug conjugates | KLK3, PTMS, DDOST | GABRA1 2205/4885GABRB2 3513/4885MEN1 1371/4885 |
| US-10710065-B2 | Polymeric materials for electrochemical cells and ion separation processes | ALG1, MLEC, MSN | GABRA1 3823/4885GABRB2 4006/4885MEN1 939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.