Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008487 | 0.71 | NPC1 (0.36) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL20008321 | 0.70 | OPRK1 (0.32) | USP2ALDH1A1LMNAALOX12MAPT | |
| SCHEMBL20008164 | 0.68 | MAPT (0.32) | MAPTHTT | |
| SCHEMBL20008179 | 0.67 | MAPT (0.31) | MAPT | |
| SCHEMBL20008522 | 0.67 | MAPT (0.30) | MAPT | |
| SCHEMBL22401233 | 0.64 | KDM4E (0.49) | USP2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL20008306 | 0.62 | — | — | |
| SCHEMBL14739172 | 0.61 | KDM4E (0.49) | USP2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL18034810 | 0.59 | ALDH1A1 (0.54) | USP2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL20009063 | 0.59 | NPC1 (0.39) | USP2ALDH1A1LMNAALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |