Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008258 | 0.91 | CYP3A4 (0.41) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL11307931 | 0.88 | SLC6A2 (0.38) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL9452735 | 0.88 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL541805 | 0.86 | ALOX15 (0.45) | SMN1; SMN2CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL19675835 | 0.85 | TAAR1 (0.39) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL8662272 | 0.83 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 | |
| SCHEMBL7428989 | 0.82 | ADRB2 (0.33) | ALDH1A1KDM4EPOLBHSD17B10 | |
| SCHEMBL18217417 | 0.82 | CYP3A4 (0.41) | SMN1; SMN2CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL11721097 | 0.78 | CYP3A4 (0.38) | SMN1; SMN2CYP3A4ALOX15CASP1CASP7 | |
| SCHEMBL7689047 | 0.78 | ALDH1A1 (0.47) | CYP1A2CYP2C9CYP2C19SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | UNIVATION TECHNOLOGIES, LLC (US) | 2019-04-09 | — | — | US | disclosed |
| EP-3286202-B1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECH LLC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20180086685-A1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086685-A1 | BRIDGED BI-AROMATIC LIGANDS AND TRANSITION METAL COMPOUNDS PREPARED THEREFROM | WEE2, WEE1, AHR | CYP1A2 644/4885CYP2C9 1395/4885CYP2C19 1944/4885 |
| US-10252967-B2 | Bridged bi-aromatic ligands and transition metal compounds prepared therefrom | WEE2, WEE1, AHR | CYP1A2 644/4885CYP2C9 1395/4885CYP2C19 1944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.