SCHEMBL8662272

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9452735	0.89	CYP1A2 (0.55)	CYP1A2CYP2C9CYP2C19KDM4EL3MBTL1
	SCHEMBL20008258	0.87	CYP3A4 (0.41)	CYP1A2CYP2C9CYP2C19L3MBTL1ALDH1A1
	SCHEMBL648261	0.85	L3MBTL1 (0.45)	KDM4ENPC1BRD4MITFL3MBTL1
	SCHEMBL20008606	0.83	CYP1A2 (0.38)	CYP1A2CYP2C9CYP2C19KDM4EL3MBTL1
	SCHEMBL7689047	0.83	ALDH1A1 (0.47)	CYP1A2CYP2C9CYP2C19L3MBTL1ALDH1A1
	SCHEMBL541805	0.83	ALOX15 (0.45)	L3MBTL1ALDH1A1POLBCASP1CASP7
	SCHEMBL19675835	0.82	TAAR1 (0.39)	CYP1A2CYP2C9CYP2C19KDM4EALDH1A1
	SCHEMBL18217417	0.79	CYP3A4 (0.41)	L3MBTL1ALDH1A1POLBCASP1CASP7
	SCHEMBL18184992	0.78	NR1I2 (0.38)	CYP1A2CYP2C9CYP2C19KDM4ENPC1
	SCHEMBL10593611	0.78	TAAR1 (0.42)	KDM4ENPC1BRD4MITFL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.