Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20008538 | 0.74 | DRD2 (0.49) | HTR6DRD2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20009117 | 0.74 | RAF1 (0.40) | NUDT1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL19529392 | 0.68 | RAF1 (0.40) | HTR6DRD2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20008460 | 0.67 | RAF1 (0.41) | HTR6DRD2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12486712 | 0.67 | SMN1; SMN2 (0.41) | NUDT1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL12486046 | 0.65 | HTT (0.44) | ALDH1A1CYP1A2SMN1; SMN2HTTMAPK1 | |
| SCHEMBL26036874 | 0.63 | PDE10A (0.62) | PDE10A | |
| SCHEMBL12486987 | 0.63 | GALR2 (0.56) | ALDH1A1HSD17B10SMN1; SMN2HTTMAPK1 | |
| SCHEMBL12484984 | 0.63 | GALR2 (0.48) | ALDH1A1SMN1; SMN2HTTMAPK1MAPT | |
| SCHEMBL20009397 | 0.62 | RAF1 (0.49) | NUDT1ALDH1A1HPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |