Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22049710 | 0.65 | TLR8 (0.45) | TLR8TLR7L3MBTL1 | |
| SCHEMBL15127655 | 0.64 | L3MBTL1 (0.44) | TLR8TLR7L3MBTL1 | |
| SCHEMBL6166426 | 0.62 | NPSR1 (0.39) | TLR8TLR7L3MBTL1 | |
| SCHEMBL27631266 | 0.62 | TLR8 (0.43) | TLR8TLR7L3MBTL1 | |
| SCHEMBL4604967 | 0.61 | KDM4E (0.35) | TLR8 | |
| SCHEMBL6166433 | 0.61 | S1PR2 (0.41) | TLR8TLR7L3MBTL1 | |
| SCHEMBL16533905 | 0.61 | PRMT5 (0.33) | — | |
| SCHEMBL20341674 | 0.61 | KMT2A (0.45) | TLR8 | |
| SCHEMBL20219465 | 0.61 | L3MBTL1 (0.61) | TLR8TLR7L3MBTL1 | |
| SCHEMBL1194029 | 0.61 | STK17A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299367-A1 | BIARYL AMIDE COMPOUNDS AS KINASE INHIBITORS | Novartis AG (CH) | 2018-03-28 | — | — | EP | disclosed |